nuBound Awarded Third Patent for Nucleotides

Nu Science Labs Inc. Announces Issuance of US Patent for Use of Nucleotides with Endurance Athletes

July 15, 2020, 09:00 AM Eastern Daylight Time

CHESTNUT HILL, MA—Nu Science Labs Inc., an innovative sports nutrition company and the developer of the nuBound® nucleotide sports recovery supplement, announced that the United States Patent and Trademark Office has issued US Patent 10,702,563 for a method to mitigate the negative effect of endurance exercise. This method uses nucleotides to enhance the recovery and performance of endurance athletes.

This new patent makes claims in connection with the demonstrated benefits of nucleotides to mitigate the negative effects arising from endurance exercise. “Issuance of this patent confirms the leadership of Nu Science Labs in understanding the effects of dietary nucleotides and applying these insights to formulations that help athletes perform better,” said Mark Connell, Founder and CEO, Nu Science Labs Inc.

Athletes seek to enhance their performance capabilities by adapting to the stress of training.  While necessary to initiate adaptation, this stress can become counterproductive. The stress response is modulated hormonally by the hypothalamic-pituitary-adrenal axis (HPA axis) and its feedback loops.

The physiological stress of endurance exercise elicits cortisol production which mobilizes energy but can also lead to catabolic effects and muscle breakdown.  Similarly, inflammation can enhance the synthesis of protein and muscle repair, however, excessive inflammation can cause tissue damage.  The proper balance between the positive and negative effects of stress is crucial to optimizing a training program.

In a clinical trial using nucleotides, conducted by William Kraemer, PhD of the Ohio State University, nuBound® users had 32 percent lower levels of cortisol and 27 less inflammation in the first hour after heavy resistance exercise.  Measured at 24 hours, the nuBound® group had 18 percent less tissue damage.

Significantly, the nuBound® group showed 41 percent higher force production capacity following exercise. Dr. Kraemer noted that, “nucleotide supplementation seems to reduce resistance exercise induced muscle damage, resulting in a greater preservation of force production capability”. The placebo group in this study took three full days to catch up in their recovery.

In addition to this third patent, Nu Science Labs has multiple additional patents filed on this and related technologies.


About Nu Science Labs

Nu Science Labs, with its product nuBound®, has pioneered the use of nucleotides to benefit the recovery of athletes.  nuBound® is NSF Certified for Sport® and currently used by athletes, coaches and trainers in the NBA, MLB, NHL, and NFL.  Consumer sales are handled via our website at: and on Amazon.  The introduction of nucleotides for athletes is the third wave of sports nutrition. nuBound® complements the benefits available from carb and protein-based recovery products.